Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 30th International Conference on Nutraceuticals and Natural Medicine Osaka, Japan.

Day :

Session Introduction

Jean-Marie poffe

Nutrition Cellulaire, Belgium

Title: GIT- Immunology

Time : 02:00 PM to 02:30 PM

Biography:

Jean-Marie poffe completed his pharmacist degree in 1976 at UCL (Brussels). In 1977, he obtained his certificate of pharmacist specialized in clinical bacteriology. For 20 years he has practiced the profession of pharmacist in his own pharmacy. Later he did specialization in nutrition and micro-nutrition and from 2005, he had started his consultations.

 

Abstract:

We will start with a histological reminder of the Gastrointestinal tract (GIT) membrane and its constituents. We will then talk about the GIT as immunologic membrane = GALT. We will review the consequences of so-called diseases of civilization. (intolerances, allergies, MIC). Then we will talk about the immune response, the differentiation of lymphocytes, the secretion of IgA, auto-illunes, the interest of pre-biotics and pro-biotics, the existing relationship between pro-biotics and immunity. It is concluded as the vital importance of the good functioning of the GIT for the well-being of patients.

 

Biography:

Sapna P Patil has completed her PhD from Institute of Chemical Technology, Mumbai. She has worked on Iridoids topic, on its extraction, isolation and chemical derivatization. She has two years of pharma industrial experience.

 

Abstract:

Iridoids are secondary metabolites produced by plants and some animals. These iridoids give colored pigments or dyes by a simple chemical process in the presence of primary amine, amino acids and protein-based substrate. The aim of the present work is mainly to study the blue colored dye, synthesized from an iridoid glycoside loganin from Strychnos nux-vomica and explore its application in textile industry. Another aim is to carry out Computer-Aided Drug Design (CADD) studies to determine the blue dye interaction with silk monomeric units. Isolated white loganin was converted to blue dye by one step chemo enzymatic reaction, wherein loganin was transformed to aglycone, loganetin which was further allowed to react with amino acids generating a blue colorant. The colorant was further studied for its application to dye proteinous fabric like wool and silk. Color strength, fastness properties and Ultraviolet protection factor were evaluated. Mordanting studies were carried out using three different mordants. The fabric was also subjected to pre-mordanting, meta-mordanting and post-mordanting studies Treated fabrics showed adequate wash, light and rubbing properties with and without mordanting. The treated silk and wool fabric showed good to very good ultraviolet protection property with mordanted fabric. The loganin, its aglycone and blue dye structures were subjected to molecular docking using Glide and SiteMap software.

 

Hadeel Saud Alshubaili

King Saud University Medical City, Saudi Arabia

Title: Sports nutrition for females and its effect on health

Time : 03: 00 PM to 03:30 PM

Biography:

Hadeel Saud Alshubaili has graduated from King Saud University, Saudi Arabia. She is the Dietitian of Metabolic and Genetics. She is certified Spinning Trainer and a Gym Instructor, she has participated in many conferences locally and internationally as a speaker.

 

Abstract:

Good nutrition will help the athletes train hard, recover quickly and adapt more effectively with less of illness or injury. Nutritional strategies need to be adopted before, during and after training to help maximize performance. Water accounts for approximately 60% of the average person’s body weight  and it varies with muscle mass, age & hydration status. Fluid loss of as little as 2% can cause early fatigue, impair performance, increase cardiac stress and increase risk of heat illness. Proper hydration is necessary before, during and after the training.

Type of diet followed by the female athletes according to life style and goals are: keto diet , low carb diet , vegan , vegetarian and paleo diet. Proteins, amino acids supplement required by the female athletes such as whey protein, casein during the pre or post workout can be covered by regular food.

The benefits of physical activity (sports) along with proper nutrition in women’s health are: T2DM (Type 2 diabetes mellitus), osteoporosis, mental health and cardiac health.

 

Location: Osaka, Japan

Session Introduction

Dheeraj Nagore

Ari Healthcare Pvt. Ltd., India

Title: Astaxanthin: A new way to fight against Alzheimer’s disease

Time : 09:30-10:00

Biography:

Dheeraj Nagore is currently a Senior Manager at Ari Healthcare Pvt. Ltd. in India. He did his MBA in Pharmaceutical Management from National Institute of Business Management, a unit of Kingstern Education. He has 10 years of experience in managing regulatory audits. He has developed more than 200 analytical methods and much toxicity profile along with validations in all categories like classical, ayurvedic, herbal and nutraceuticals. He is an expert in vendor development of different type of API and its evaluation and standardization. He has published more than 31 research papers in national and international scientific journals

Abstract:

Even though the precise molecular mechanisms responsible for aging of the brain cells at the end of the day landed upon significant alterations in some cognitive domains and neurodegenerative diseases are still being unexplained. Astaxanthin is a reddish pigment that belongs to a group of compounds called as carotenoids. It occurs naturally in some algae and causes the pink or red color in salmon, trout, lobster, shrimp and other seafood. This compound dramatically grabs the popularity since last few decades and many researchers are loved to study the molecule for the Alzheimer’s and other related neurodegeneration. Results from the many research studies are reported and suggest a neuroprotective property which covers anti-inflammatory, anti-apoptotic and anti-oxidant effects as well as the prospective action to support neural plasticity. These promising mechanisms of actions involve Astaxanthin as a promising therapeutic agent in the treatment of neurodegenerative disease. It is believed that nutritional supplementation of Astaxanthin for 12 weeks improved psychomotor speed and processing speed, as measured by the CNSVS test, which is related to the ability to comprehend, and accomplish multifarious tasks rapidly and precisely. Research studies have also confirmed that Astaxanthin can easily cross the blood-brain barrier to safeguard the brain from acute injury and chronic neurodegeneration. Astaxanthin is an outstanding candidate for managing neurological diseases. It is necessary to continue further assessments through all facets of Astaxanthin’s protective action and essential mechanisms, which may ultimately result to get Astaxanthin as a novel neuroprotective agent in the treatment of Alzheimer’s dementia.
 

Santiago Ini

Technion Israel Institute of Technology, Israel

Title: Nutraceuticals from bench to delivery

Time : 10:00-10:30

Biography:

Santiago Ini has received his PhD in Organic Chemistry from Faculty of Chemistry at the Technion. He has also worked as a Postdoctoral candidate in Organometallic Chemistry and Imprinting polymers at UC Berkeley followed by a MBA. Prior joining the Technion Technology Transfer Office as a Director of Business Development in Life Science, he played a role as a top Manager at the Chemistry Division of Teva Pharmaceutical industry, Enzymotec and Algatechnologies providing innovation and leadership in the life science sector. He is an author of several scientific articles and more than 40 patents. He is the Founder of Mental Heal, a company that develops a drug for the treatment of schizophrenia and Glaucopharm, a company dealing with the treatment for glaucoma

Abstract:

The demand for nutraceuticals is increasing everyday due to the greater market awareness and acceptance. Product taste, texture and packaging matter when it comes to consumer purchasing decisions, although taste is the most important driver of the nutraceutical product. Many ingredients have a bland taste or change the food’s texture once they are added. This is a particular problem for omega-3s. Also, some nutrients are incompatible with base products. For example Astaxanthin or Vitamin E are not water-soluble and is difficult to mix into existing products. Stability and shelf life are important factors as well since many nutrients are unstable and sensitive to light and can react with other ingredients to degrade nutrients. The current Technion research provide methods for entrapment of hydrophobic nutraceuticals within re-assembled casein micelles, protecting the bioactive during processing, shelf life and digestion, providing high bio-availability. New technologies are suitable for excellent protection against EGCG deterioration (including neutral and higher pH) in any food. Novel technology for the use of sugar beet pectin nanoparticles, commercially sourced to entrap and protect poor water soluble bioactive in aqueous solutions.
 

Vaibhav D Aher

Shree Swami Samarth Institute of Pharmacy, India

Title: Mushroom immunomodulators: Medicinal effects

Time : 10:00-10:30

Biography:

Vaibhav D Aher has received his Master’s degree in Pharmaceutical Biotechnology and completed PhD from National Institute of Medical Sciences. He has Postdoctoral studies from Defence Research Laboratory, Defence Research and Development Organization (DRDO), India and University of Arkansas for Medical Sciences, USA. He has published more than 15 papers in reputed journals and has been serving as a Reviewer of repute. His research experience is in the field of immunomodulatory and gentoxicity studies.
 

Abstract:

Immunomodulators are key components in the modern health and wellness industries, reflecting the fact that the immune system is the first barrier for disease prevention. Recently many bioactive compounds have been isolated from different types of mushrooms. Among these immunomodulators have gained much interest based on the increasing growth of the immunotherapy sector. In clinical practice, immunomodulators are usually classified into immunosuppressants, immunostimulants and immunoadjuvants. They are even used as prodrugs or prophylactic medicine for healthy people. More than 50 known mushrooms harbor immune regulating organic compounds of highly diversified molecular weight and structure. Few mushrooms with immunomodulator activities exhibit stimulating activities for both innate and adaptive immune systems. They proliferate and activate innate immune system components such as Natural Killer (NK) cells, neutrophils and macrophages and stimulate cytokines expression and secretion, cancer and infectious diseases. These cytokines in turn activate adaptive immunity through the promotion of B cells for antibodies production and stimulation of T cell differentiation to T helper cells, which mediate cell and humoral immunities, respectively. Based on their high molecular weight, mushroom polysaccharides are not able to penetrate the immune cells to activate immune cells directly. Thus stimulation mechanism of polysaccharides involves different cell receptors such as dectin-1, Complement Receptor 3 (CR3), Lactosylceramide (LacCer) and Toll-Like Receptor (TLR)2. In such cases, the effectiveness of polysaccharides is governed by their binding affinity to immune cell receptors. In general, mushroom immunomodulators are classified into four main groups: Immunomodulatory lectins, immunomodulatory terpenes and terpenoids, immunomodulatory polysaccharides and Fungal Immunomodulatory Proteins (FIPs).
 

Biography:

Wijerathne is currently pursuing his Bachelor of Medicine and Bachelor of Surgery degree from University of Colombo. He is the Captain of the Karate team of University of Colombo. He studied three martial arts; Karate, Wing Chun and Taekwondo.
 

Abstract:

Method: Cross sectional study was carried out among 178 national level athletes aged 18-35 years representing karate, swimming, wrestling, volleyball, weight lifting (indoor) netball, rugby, track and field athletes (outdoor). Self-administered questionnaire obtained data on knowledge, attitude and practices on dietary pattern, hydration and supplements. Body composition (body mass index and body fat percentage) was determined using stadiometer, weighing scale and body impedance analyzer. Results: Practices were poor; consuming fast food (88.8%), missing meals (56.8%), improper meal timing (65.3%) and inadequate hydration during practices (73.8%). Majority (53.4%) had recommended BMI, however only 15.3% had recommended body fat. Majority (60.1%) had adequate overall knowledge on sports nutrition. Knowledge within subcategories varied, where most were of satisfactory knowledge with regard to dietary intake (59.6%) and supplements (55.6%), but not hydration (35.4%). Overall attitudes were positive (58.4%). Compared to outdoor sports, indoor sports significantly associated with improper timing of meals (indoor 65.6%, outdoor 40.6%; p<0.01), missing meals (indoor 64%, outdoor 40%; p<0.01), adequate hydration (indoor 66.3%, outdoor 84.3%; p<0.01) and less supplement consumption (indoor 68.9%, outdoor 48%; p<0.01). Compared to females, males had improper meal timing (males 62.7%, females 42.6%; p<0.05), adequate hydration (males 32.1%, females 16.1%; p<0.05) and recommended body fat percentage (males 19.4%, females 7.8%; p<0.05). Less experienced athletes had adequate BMI (less 63.6%, more 44.4%; p<0.05) but consumed more energy drinks (less 70.3%, more 38.8%; p<0.01). Athletes with higher education level (47.3%) consumed supplements compared to lower educational level (32.3%; p<0.05). Knowledge was not associated with any practices.